WEBVTT

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>> Thank you Britney.

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I will introduce our next
speaker, William Suk, Director
Superfund

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Research Program.

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>> Thank you Heather.

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Hello, welcome to the Superfund
research program, funding

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opportunity web seminar.

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I am the director of the
Superfund research program here
at

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NIEHS. Thank you for your
participation.

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We see this as an opportunity to
reach out to potential grantees,

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answer questions about program
and provide contact information
for

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future questions.

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>> We are very pleased that
there is so much interest in our
program.

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Over 100 registrants. From a
quick survey of the

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participant list, it appears we
have individuals who might be
new,

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to the SPR and its funding
mechanism, as well as a number

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of veteran applicants, probably
well-versed in the program. This

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reason, we have designed the
presentation to provide a little
something for

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everyone. We have highlighted
the nuts and bolts about the

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P42 funding opportunity, and
also providing some tips to
share about

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the nuances of putting together
a competitive application.

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>> My feeling is that the real
trick

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of running together a
competitive application, is to
contact

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us early on the process, and to
keep communication open to as
you

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put together your application.

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>> We have a whole room full of
staff as

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[ Indiscernible ]. We are ready
to present a brief overview of
the

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P 42 application and process.

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>> We will have time for live
Russians at the in, please

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have your questions ready.

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>> -- Questions.

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>> This slide shows the SPR
registration

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under the Superfund amendments
and reauthorization act.

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It allows the flexibility to
create university-based centers

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to conduct scientific research
to address a wide array

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of scientific uncertainties,
facing the exposure to hazardous

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substances.

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>> The full title is the NIEHS
Superfund hazardous substance

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research program. The scope of
the SPR is taken directly from

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[ Indiscernible ] -- SARA.

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Including advanced

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techniques for the detection,
assessment and evaluation of the
human health

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effects and hazardous
substances.

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Methods to assess the risks to
human health presented

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by hazardous substances.

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Methods and technologies to
detect hazardous substance in
the

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environment. Basic biological,
chemical and physical methods to
reduce the

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amount of toxicity of hazardous
substances.

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>> Complex problems related to
hazardous substance require the

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expertise of multiple
biomedical, and environmental
science and

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engineering disciplines.

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>> In addition to our mandates,
our

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program is guided by an
strategic plan. Plan stresses
are continued

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dedication to program relevance
and identifies our key

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stakeholders as EPA, ATSDR, as
well as other

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agencies and entities,
responsible sites by the
communities living

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near the sites.

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>> We also highlight the
importance of program research
to

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achieve impact and promote
innovation.

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>> During today's visitation, I
encourage you to

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consider how to design a
scientific study --

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and centers that are relevant to
key stakeholders. And bring
innovation

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and innovative research the
practice, reducing

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hazardous substances, preventing
exposures.

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>> Applicants are encouraged to
refer to the SRP strategic plan,

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you can see the link on the
screen on the bottom of the
slide. It describes

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and defines the objective and
goals of the SRP, in order to
address

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mandates.

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>> Before I move on I want to
mention

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that the SRP has several funding
mechanisms.

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I am also providing a link to
the SRP website for you to
access other

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funding opportunities. Today's
call will focus only on the P42
multi

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project center funding
opportunity.

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>> With that, I will pass it on
to Heather

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Henry, Program Administrator.
Thank you all for your
anticipation.

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>> -- Participation.

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>> Thank you. We will cover most
of the aspects during this
presentation,

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by no means is this all of the
information. Thank goodness

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we will not read the entire
thing.

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It is important that you read
the entire resource that we
provide

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on our website. Those resources
include suggested research,

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activities, tips and additional
resources.

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Again this webinar presentations
meant to complement the

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RFA and address questions. We
will not have time to go over it
in extensive

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detail.

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>> To begin, the goal of the
Superfund research program is

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to improve public health by
supporting integrative, multiple
--

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multidisciplinary research.
Fundamental found -- sound

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science to inform the risk
assessment and

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remediation management processes
bring expertise of multiple
biomedical

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and environmental science and
engineering disciplines to
address scientific

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uncertainties facing the
national Superfund program

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>> Also problems related to

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sites impacted by hazardous
substance, require the expertise
of environmental

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disciplines.

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Applicants responding to this

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funding opportunity
announcement, well-designed

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-- design a science for science
and engineering.

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Before we continue I also want
to reiterate the importance of
reaching

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out to the staff if you are
considering applying to this
RFA. Contact us

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early in the process to ensure
you get a response. We know it
is a

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lot of work for one of these
applications together, we want
to help you with

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your success with your endeavor.

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>> Here we have listed many key
dates.

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We hope that you print this out
and post it somewhere.

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It is open, the earliest receipt
date November 19. The letter

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and intent due date November 19.
Please be sure you submit
everything

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on time. We will hear more about
that later, particularly

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from our scientific review
officer.

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>> SRP center grants, support

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oriented research. Centers
consist of multiple integrative
projects,

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representing environmental
science and engineering.

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Administrative research
translation, data analysis,
community

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engagement, and training
coordination, as well

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as research support.

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>> Interaction is necessary to
resolve a problem the sender

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opposes.

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Furthermore, integration and

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interaction should be
demonstrated between biomedical

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and environmental science of
engineering project, as they
contribute to the

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goals in addition, the research
emanating from the center, and

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it should be incorporated into
sustainable solutions that take
into account

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environmental, social and
economic issues.

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>> SRP supports
transdisciplinary research,
adapting

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technology and purchasing one
field and applying

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them to other fields in order to
solve challenging environmental

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health problems.

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Forward-looking anticipatory
research is critical to identify
and address

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future stakeholder needs.

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>> This slide

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summarizes many aspects to
consider when you think about
the

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SRP center grants. Wayne fact
identified these in the

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scope of the grant.

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The scope of the center grants
to be defined by the

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SRP mandates, which are listed.

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We encourage you to pay
attention to those as you put

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together your application.
Research and supporting
activities may

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utilize a variety of cultures to
achieve SRP mandates. We ask you

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to please review the suggested
research topics and

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activities documented.

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And we have other resources on
how you can have a mandate for
the

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SRP. It is important that you do
-- review

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the strategic plan that
information on how weight center
would include

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a scope of relevance to
Superfund, impacts stakeholders

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and innovation,
which the -- which should be
[ Indiscernible ]

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The SRP is not as site-specific
program, the most broad sense

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having substance and would be
relevant to SRP. These
substances may

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include hazardous substances
farmed, one

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might refer to the comprehensive
environmental liability act. And

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we have the website for more
information.

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Others is hazardous takedown
products from the substances
that

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might be found at other
hazardous waste sites, as well
as processes

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and metabolites of the
substances, breaking down
products after

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exposure and environmental
animal models.

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>> A lot of information is found
in

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the additional resource link. We
also have a list

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of hazardous substances,
emerging contaminants,

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that have been suggested by our
sister agency.

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When you are looking for topics
for your

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center application, important to
consider automatic balance. --

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Please note, when you decide
what your center will support,
you

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can see what we are already
funding in the area. A link

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is provided on this page.

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>> Finally in the broadest
sense, the center should
demonstrate a

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link to Superfund.

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>> The importance of the
application.

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This chart shows you an
application should consist of
these

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following components.
Environmental science and
engineering, including

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research translation, data
analysis, research

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experience and training
coordination core, those that
I've mentioned,

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all required. Optional would be
research support core. And

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we want to note that
applications must successfully

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meet the minimal requirement,
minimum of two environmental and

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science engineering, as well is
the four required core. But

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the center cannot exceed a total
of 11 projects. In addition,

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new renewal proposals and
re-submissions up to 1.75
million

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per year direct cost for 5
years.

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>> Just to point

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out, some cost limitations.

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[ Indiscernible ] administrative
community engagement and
training

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coordination. There is not a
budget set for data management
or research

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support or the projects. And
this fits together -- an overall
20%

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of the total center budget for
the three course listed,

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AC, RETCC,

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AC, and any research support.

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>> Now we will shift gears and
we will

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tell you more about the overall
component and what you should
include.

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This is coming directly from the
RFA. These are points

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that we would like to emphasize
to you.

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>> The overall is a component of
the application.

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It is summarizing the overall
center and what is proposing

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to accomplish.

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Please make a good connection
between your

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center and the SRP mandate.

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We often encourage you to
include how the center plans to
solve problems

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related to health, risk,
remediation and hazardous
substance, which is

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the mandate. And we like for --
especially in your aspect,

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-- abstract. A generic
description of components, and

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overall indication of the
proposed signs and what they
propose to

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accomplish.

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>> Including hazardous
substances being evaluated,

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how they are relevant to the SRP
and Superfund, and in general

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if you are working on a study
site, the research approach you
are using,

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the model organism and
biological system, disease
pathways you are

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targeting, and in addition, this
section should highlight aspects

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of the application particularly
innovative or paradigm shifting.

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>> Solving problems and the role
of

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each project contributing to
resolving the problems stated

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the application the primary
activity should be

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integrated into the description,
and the benefits of the center,

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improving health, and it should
also be included

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in addition, each specific aim
supported by a brief description

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of how that will be accomplished
through interactions of the
projects.

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You want to include the
expertise that

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you have to accomplish these
goals, the innovation of the
science and

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strength of the approach shall
be described.

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>> There are some

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sections recommended in the
overall component, these are the
significance,

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relevance to mandates, and the
research

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team, innovation, approach and

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environment and center
integration please refer

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to RA for the overall good of
the center -- RFA.

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>> A few things that we want to
know are the other attachments
that

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would be included. There is a
specific way to do it. And

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it is outlined in the RFA,
essentially the filename
provided

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for each attachment will be the
same name used for the bookmark

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the application.

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This is something that we want
to tell you, because it will
make it

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easier to reference your
application, once it is put
together as

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00:16:25.000 --> 00:16:28.000
a PDF if you take it to heart.

271
00:16:28.000 --> 00:16:33.000
>> Specific descriptions
provided for each

272
00:16:33.000 --> 00:16:36.000
attachment within the RFA.

273
00:16:36.000 --> 00:16:40.000
We want to point out new to the
RFA this year is a table

274
00:16:40.000 --> 00:16:43.000
of integration with the center.

275
00:16:43.000 --> 00:16:44.000
There are illustrations on the
website, on the tips for
applicants

276
00:16:44.000 --> 00:16:47.000
page.

277
00:16:47.000 --> 00:16:51.000
>> In addition, there is an
overall center resource sharing

278
00:16:51.000 --> 00:16:57.000
plan, and in this current RFA,
you are asked to include within

279
00:16:57.000 --> 00:17:02.000
that research sharing plan, in
the overall component, a summary

280
00:17:02.000 --> 00:17:05.000
of the center data management
and analysis. This is a general
description

281
00:17:05.000 --> 00:17:09.000
of the type of data expected to
be generated from the center. It

282
00:17:09.000 --> 00:17:14.000
is a synopsis of the most data
management and sharing
activities

283
00:17:14.000 --> 00:17:20.000
in this section, applicants they
wish to highlight, anticipated
opportunities

284
00:17:20.000 --> 00:17:23.000
between project and core.

285
00:17:23.000 --> 00:17:26.934
Note, there is a full data
management analysis core, but it
is a separate

286
00:17:26.934 --> 00:17:30.934
component. This little section
is just a summary of overall
happening,

287
00:17:30.934 --> 00:17:34.934
in terms of data management and
sharing.

288
00:17:34.934 --> 00:17:40.934
>> Let's go to the next slide.

289
00:17:40.934 --> 00:17:45.934
We did share some examples of
the overall section. We request

290
00:17:45.934 --> 00:17:47.934
a table of changes.

291
00:17:47.934 --> 00:17:53.934
That is important for any
renewal or resubmission
application.

292
00:17:53.934 --> 00:17:58.934
It is a table of portal
utilization, and

293
00:17:58.934 --> 00:18:03.934
research approaches. It is very
helpful for the reviewer as they

294
00:18:03.934 --> 00:18:07.934
can to the overall center,
because it gives an indication

295
00:18:07.934 --> 00:18:10.934
of how there is interaction, and
between the different projects

296
00:18:10.934 --> 00:18:14.000
and course.

297
00:18:14.000 --> 00:18:20.000
>> On our next table I want to
point out, this

298
00:18:20.000 --> 00:18:21.000
is a new table.

299
00:18:21.000 --> 00:18:24.934
We think it will be helpful for
reviewers to understand

300
00:18:24.934 --> 00:18:28.934
how the center proposes to have
integration between projects and

301
00:18:28.934 --> 00:18:32.934
course shown is a very generic
demonstration of what we

302
00:18:32.934 --> 00:18:35.934
are conceiving by the type of
table.

303
00:18:35.934 --> 00:18:40.934
Essentially, we would like for
the applicant to demonstrate

304
00:18:40.934 --> 00:18:44.934
how projects are integrated, and

305
00:18:44.934 --> 00:18:48.934
the nature of the integration
between project and core.

306
00:18:48.934 --> 00:18:52.934
>> Lastly, I did mention this
previously,

307
00:18:52.934 --> 00:18:56.934
this is another snapshot of what
we are talking about in regard
to

308
00:18:56.934 --> 00:18:59.934
the resource sharing plan.

309
00:18:59.934 --> 00:19:05.934
>> At this point, this includes
the discussion of the overall
section.

310
00:19:05.934 --> 00:19:08.934
I will pass it up to Danielle.

311
00:19:08.934 --> 00:19:14.000
>> Thank you Heather. First we
will focus

312
00:19:14.000 --> 00:19:19.000
on the research project. You met
[ Indiscernible ] the center

313
00:19:19.000 --> 00:19:23.000
research project. And
emphasizing the balance of basic
and research

314
00:19:23.000 --> 00:19:28.934
contributing to the
problem-based solution goals,

315
00:19:28.934 --> 00:19:32.934
the center problems should be
addressed by the contribution

316
00:19:32.934 --> 00:19:38.934
projects, and within each
project having the necessary
biomedical

317
00:19:38.934 --> 00:19:43.934
expertise to address the centers
central problems or themes.

318
00:19:43.934 --> 00:19:47.934
>> Let's start the biomedical
research project.

319
00:19:47.934 --> 00:19:53.934
The DMR. As noted in the -- BMR.

320
00:19:53.934 --> 00:19:57.934
Is required and should address
biomedical related

321
00:19:57.934 --> 00:20:03.934
implications of hazardous
substance we provide a list and

322
00:20:03.934 --> 00:20:08.934
suggested research and
activities document, qualifying

323
00:20:08.934 --> 00:20:11.934
for biomedical topics.

324
00:20:11.934 --> 00:20:16.000
A minimum of [ Indiscernible ]

325
00:20:16.000 --> 00:20:20.000
engineering projects required
and shouldn't address

326
00:20:20.000 --> 00:20:23.000
environmental science or
implications of hazardous
substance. They are

327
00:20:23.000 --> 00:20:27.934
integral to protection of human
health, [ Indiscernible ]
predicting

328
00:20:27.934 --> 00:20:30.934
and preventing exposure.

329
00:20:30.934 --> 00:20:36.934
We provide suggestions and
activity documents for topic
suggestions.

330
00:20:36.934 --> 00:20:38.367
I will also provide additional

331
00:20:38.367 --> 00:20:40.934
information about a new
requirement, the environmental

332
00:20:40.934 --> 00:20:46.934
science and engineering project
in the. For now we are keeping

333
00:20:46.934 --> 00:20:50.934
focus on types of projects and
what they require.

334
00:20:50.934 --> 00:20:55.934
For both types of project, they
should be standalone,

335
00:20:55.934 --> 00:21:00.934
hypothesis driven or
[ Indiscernible ]. It should
contribute to the

336
00:21:00.934 --> 00:21:04.934
overall center objective,
providing a clear step four

337
00:21:04.934 --> 00:21:08.934
identifying solutions, solving
goals of the center each objects

338
00:21:08.934 --> 00:21:15.000
relate to the SRP mandate,
health effects, risk detection
and remediation.

339
00:21:15.000 --> 00:21:19.000
Trying connection and relevance
to Superfund as appropriate.

340
00:21:19.000 --> 00:21:23.934
Please make sure to include
which hazardous absence of being
evaluated,

341
00:21:23.934 --> 00:21:26.934
which research approaches use,
and the exposure

342
00:21:26.934 --> 00:21:31.934
context as appropriate.
Including information about the
model

343
00:21:31.934 --> 00:21:35.934
organism, biological system,
disease pathway, environmental
media, etc.,

344
00:21:35.934 --> 00:21:39.934
as well as any study sites that
you're working on that is
applicable.

345
00:21:39.934 --> 00:21:45.934
In addition, the project should
highlight applications that are

346
00:21:45.934 --> 00:21:48.934
innovative, paradigm shifting.

347
00:21:48.934 --> 00:21:50.934
Plans for engaging stakeholders
and communities

348
00:21:50.934 --> 00:21:53.934
if applicable should be
included, and important to
highlight the

349
00:21:53.934 --> 00:21:58.934
significant of the research
project, the expertise and
innovation of

350
00:21:58.934 --> 00:22:01.934
the science, details of the
experimental approach,

351
00:22:01.934 --> 00:22:05.934
including rationale for the
methodology, the strains of the
research

352
00:22:05.934 --> 00:22:08.934
environment, a timeline for
project completion, as well as a
description

353
00:22:08.934 --> 00:22:15.000
of how the project contributes
to the overall SRP center. As
such

354
00:22:15.000 --> 00:22:20.000
the subsections are recommended
significant and relevant to SRP

355
00:22:20.000 --> 00:22:24.934
mandates and Superfund
investigators, innovation,
approach and center

356
00:22:24.934 --> 00:22:28.934
integration. It is important to
explain how the project is
advances

357
00:22:28.934 --> 00:22:33.934
knowledge and provides research,
technologies utilized improve
human

358
00:22:33.934 --> 00:22:37.934
health, risk assessment and/or
improve the quality

359
00:22:37.934 --> 00:22:40.934
of the environment, and how the
project provides rigorous
scientific

360
00:22:40.934 --> 00:22:43.934
data that may be used for
effective decision-making by
stakeholders.

361
00:22:43.934 --> 00:22:47.934
Research facility and
additional's or including,

362
00:22:47.934 --> 00:22:51.934
and other features that support
so late collaborative

363
00:22:51.934 --> 00:22:57.934
and multidisciplinary research
approaches and it should all be
included.

364
00:22:57.934 --> 00:23:02.934
Applicants having a description
of the relation to the
overall's,

365
00:23:02.934 --> 00:23:05.934
clearly spending the relevance
of the project the goals

366
00:23:05.934 --> 00:23:08.934
of the overall, and how this
project integrates with other
project and

367
00:23:08.934 --> 00:23:15.000
course email-you may refer to
your table integration,
attachment

368
00:23:15.000 --> 00:23:18.000
-- this part of the overall
component. Again, see the

369
00:23:18.000 --> 00:23:22.000
overall section brother
attachment applicants required
to comply with

370
00:23:22.000 --> 00:23:26.934
the instructions for the
research sharing plan is
provided in the

371
00:23:26.934 --> 00:23:31.934
application guide. Projects are
expected to include within data

372
00:23:31.934 --> 00:23:35.934
management plan, within data
sharing plan a data management

373
00:23:35.934 --> 00:23:38.934
plan, investigator translation
plan.

374
00:23:38.934 --> 00:23:44.934
The data management plan, and
research plan,

375
00:23:44.934 --> 00:23:49.934
the data management -- excuse
me.

376
00:23:49.934 --> 00:23:51.934
That data management plan cross
reference in the data management

377
00:23:51.934 --> 00:23:56.934
and analysis core, and to be
sure to work with your meter and
your

378
00:23:56.934 --> 00:23:59.934
-- DMAC on the section.

379
00:23:59.934 --> 00:24:03.934
The investigative initiated
translation and cross reference
in the administrative

380
00:24:03.934 --> 00:24:06.934
core research translation
function.

381
00:24:06.934 --> 00:24:10.934
Any description and/or checklist
of the data management,

382
00:24:10.934 --> 00:24:19.000
and examples of investigator
initiated activities are
provided for reference,

383
00:24:19.000 --> 00:24:23.000
and it is within the document on
the website listed on the slide.

384
00:24:23.000 --> 00:24:27.934
>> We

385
00:24:27.934 --> 00:24:31.934
also added further guidance to
the environmental science and
engineering

386
00:24:31.934 --> 00:24:34.934
addicts in the current RFA.

387
00:24:34.934 --> 00:24:37.934
As you all know, the SRP
recognizes the importance of new
environmental

388
00:24:37.934 --> 00:24:41.934
science and engineering purchase
to reduce the amount of toxicity

389
00:24:41.934 --> 00:24:44.934
in hazardous substances in the
environment.

390
00:24:44.934 --> 00:24:50.934
Costing between remediation
approaches through new

391
00:24:50.934 --> 00:24:55.934
mediation platforms, assessing
for an important contribution to
have

392
00:24:55.934 --> 00:25:00.934
cleanup of hazardous substance
and preventing exposure to all
applicants

393
00:25:00.934 --> 00:25:02.501
are required in this RFA, to

394
00:25:02.501 --> 00:25:04.934
include at least one
environmental science

395
00:25:04.934 --> 00:25:09.934
and engineering logic that
supports SRP for mandate, which

396
00:25:09.934 --> 00:25:15.000
is basic biological chemical
health and physical methods to
reduce

397
00:25:15.000 --> 00:25:17.000
the amount of toxicity.

398
00:25:17.000 --> 00:25:21.000
For more information on how to
develop one of these projects,
make

399
00:25:21.000 --> 00:25:24.934
sure you review the RFA section
title,

400
00:25:24.934 --> 00:25:29.934
scope of the SRP center grant,
and reviewed the digestive
research

401
00:25:29.934 --> 00:25:32.934
and activities document which is
topics available to meet

402
00:25:32.934 --> 00:25:36.934
the requirements of mandate. If
you have any questions about
whether

403
00:25:36.934 --> 00:25:40.934
or not your project qualifies,
please reach out to the SRP
staff

404
00:25:40.934 --> 00:25:44.934
to ensure that your project is
responsive to the RFA.

405
00:25:44.934 --> 00:25:49.934
>> These are some tips that we
have

406
00:25:49.934 --> 00:25:51.934
together.

407
00:25:51.934 --> 00:25:53.934
For example, center should be
very judicious in assembling
research

408
00:25:53.934 --> 00:25:59.934
project. I center should, with
projects, keep a clear focus on
not try

409
00:25:59.934 --> 00:26:02.934
to do too much include projects
with the most sales connection
to

410
00:26:02.934 --> 00:26:08.934
the centers problem-solving pain
please note, projects are
similar

411
00:26:08.934 --> 00:26:14.000
to an NH grant, typically
written in an

412
00:26:14.000 --> 00:26:19.000
[ Indiscernible ] staff. For
those that are not family, this
is an

413
00:26:19.000 --> 00:26:24.000
investigator grant. Also please
keep in mind we are still in

414
00:26:24.000 --> 00:26:30.000
[ Indiscernible ] time consider
coming under budget, as under
the 11

415
00:26:30.000 --> 00:26:35.000
component limit especially true
for new center proposals.
Another

416
00:26:35.000 --> 00:26:39.000
tip, cross reference interaction
between projects and course, and

417
00:26:39.000 --> 00:26:44.000
they should be consistent
throughout the refer to the
table of integration

418
00:26:44.000 --> 00:26:50.000
with center to overall those
highlighted interactions. To
avoid

419
00:26:50.000 --> 00:26:54.000
jargon. Especially with titles
and general audience. Do not
assume

420
00:26:54.000 --> 00:27:00.000
all reviewers will be
well-versed only those assigned
will

421
00:27:00.000 --> 00:27:05.000
be well-versed. Pete -- P 42
reviewers have brought
expertise.

422
00:27:05.000 --> 00:27:08.000
Make sure you write your titles
for a general

423
00:27:08.000 --> 00:27:13.000
audience, right specific aims
for technical experts. Do not
forget

424
00:27:13.000 --> 00:27:17.000
to define abbreviations we
highly encourage you to visit
the

425
00:27:17.000 --> 00:27:20.000
website on plain language.

426
00:27:20.000 --> 00:27:23.000
>> The RFA has suggestions for

427
00:27:23.000 --> 00:27:27.934
any projects community-based,
and please look out for that. I
will

428
00:27:27.934 --> 00:27:31.934
turn it over to Michelle
[ Indiscernible ].

429
00:27:31.934 --> 00:27:34.934
>> -- Heather Henry, Program
Administrator.

430
00:27:34.934 --> 00:27:40.934
>> We will start with the

431
00:27:40.934 --> 00:27:45.934
administrative core. Which is
required in the P 42 application
including

432
00:27:45.934 --> 00:27:52.934
research translator coordinator
and center administrator.

433
00:27:52.934 --> 00:27:54.934
And a center administrator will
provide leadership and guidance

434
00:27:54.934 --> 00:27:59.934
to ensure that emphasis of
findings and that it is and
research projects

435
00:27:59.934 --> 00:28:04.934
and use toward addressing the
central problems, objective
proposed by

436
00:28:04.934 --> 00:28:08.934
the center. The application will
include a description of

437
00:28:08.934 --> 00:28:11.934
lines of communication of the
center administrator, the
research translation

438
00:28:11.934 --> 00:28:17.000
coordinator, and the core
leaders.

439
00:28:17.000 --> 00:28:20.000
They should also be a
description of the mechanism to
be used to encourage

440
00:28:20.000 --> 00:28:23.934
and ensure the integration and
interaction between the
biomedical

441
00:28:23.934 --> 00:28:28.934
and environmental science and
engineering project. There
should be a plan

442
00:28:28.934 --> 00:28:33.934
for data sharing and analysis
activities, integration across

443
00:28:33.934 --> 00:28:37.934
disciplinary research,
overseeing a fiscal and resource
management,

444
00:28:37.934 --> 00:28:39.934
providing quality management.

445
00:28:39.934 --> 00:28:44.934
The course should describe a
strategy for personnel
management changes,

446
00:28:44.934 --> 00:28:48.934
and as applicable, secession
plan. It should provide

447
00:28:48.934 --> 00:28:53.934
points of contact for regulatory
SRP conference calls

448
00:28:53.934 --> 00:28:58.934
are webinars on research
translation, community
engagement, and data

449
00:28:58.934 --> 00:29:04.934
analysis. I mentioned the
research translation
coordinator, this

450
00:29:04.934 --> 00:29:09.934
is new to this P 42.

451
00:29:09.934 --> 00:29:14.000
All applicants required to
include user translation as a
part of the

452
00:29:14.000 --> 00:29:16.000
administrative core function.

453
00:29:16.000 --> 00:29:20.000
This will help to facilitate
coordination between the results

454
00:29:20.000 --> 00:29:24.934
accomplishments and the
implications of the center's
research stakeholders,

455
00:29:24.934 --> 00:29:32.934
including NIEHS and other
applicable stakeholders

456
00:29:32.934 --> 00:29:36.934
in a context that makes it
applicable to the targeted
audience. As you

457
00:29:36.934 --> 00:29:41.934
might recall in the previous RFA
we had a separate translation.

458
00:29:41.934 --> 00:29:46.934
It is now contained in the
administrative core, the SRP is
committed to foster

459
00:29:46.934 --> 00:29:51.934
translation of scientific
accomplishment to support
mandate.

460
00:29:51.934 --> 00:29:55.934
The definition remains the same
as in previous RFA,

461
00:29:55.934 --> 00:30:01.934
communicating, facilitating the
use of research findings,
emanating

462
00:30:01.934 --> 00:30:05.934
from the center in a manner most
appropriate for the application.

463
00:30:05.934 --> 00:30:08.934
And the advancement research
object.

464
00:30:08.934 --> 00:30:11.934
Therefore the administrative
portion of a description for the

465
00:30:11.934 --> 00:30:15.000
following research translation
objectives.

466
00:30:15.000 --> 00:30:20.000
Communicating within SRP and SRP
staff partnerships

467
00:30:20.000 --> 00:30:23.934
with government agencies,
technology transfer, information
dissemination

468
00:30:23.934 --> 00:30:28.934
to other end-users.
Additionally, the administrative
core should

469
00:30:28.934 --> 00:30:33.934
come out investigator initiated
research translation, therefore

470
00:30:33.934 --> 00:30:38.934
the administrative core has a
critical role in assisting
project

471
00:30:38.934 --> 00:30:41.934
core members and translating the
research outcomes and activities

472
00:30:41.934 --> 00:30:46.934
to appropriate audience,
ensuring the act and timely use
of products,

473
00:30:46.934 --> 00:30:48.934
and sharing some findings.

474
00:30:48.934 --> 00:30:52.934
The administrative core will be
responsible

475
00:30:52.934 --> 00:30:57.934
for ensuring that updates are
made to the optional SRP data
collection

476
00:30:57.934 --> 00:31:00.934
tool, the URL is on the slide.

477
00:31:00.934 --> 00:31:04.934
And the career track database,
designating points of contact

478
00:31:04.934 --> 00:31:08.934
responsible for reporting
information, as well as a plan
for frequent the

479
00:31:08.934 --> 00:31:12.934
of reporting a point of contact
should be indicated

480
00:31:12.934 --> 00:31:19.000
in the research strategy section
for the regular SRP, community

481
00:31:19.000 --> 00:31:24.934
engagement, data and task
management. Examples of

482
00:31:24.934 --> 00:31:29.934
investigative initiated
activities are provided in the
suggested

483
00:31:29.934 --> 00:31:35.934
research and activities document
on the website you see

484
00:31:35.934 --> 00:31:36.934
on the slide.

485
00:31:36.934 --> 00:31:42.934
The SRP optional data collection
tool allows grantees to inform
staff,

486
00:31:42.934 --> 00:31:47.934
centered activities, webinars,
interactions with

487
00:31:47.934 --> 00:31:52.934
stakeholders, training,
investigative awards, news
articles, and publication.

488
00:31:52.934 --> 00:31:56.934
The database can be found at the
link

489
00:31:56.934 --> 00:31:58.934
on the right, please note,
permission to use the databases
only provided

490
00:31:58.934 --> 00:32:01.934
after an award is made.

491
00:32:01.934 --> 00:32:07.934
>> Two also eight and achieve

492
00:32:07.934 --> 00:32:10.934
the goals, the administrative
court is required to establish

493
00:32:10.934 --> 00:32:15.000
an external advisory committee,
to provide

494
00:32:15.000 --> 00:32:19.000
guidance to the center director
in the following areas.
Scientific

495
00:32:19.000 --> 00:32:23.000
merit, the relevance and
importance of

496
00:32:23.000 --> 00:32:26.934
the individual component for the
center, the integration of
research

497
00:32:26.934 --> 00:32:32.934
across disciplines, the
effectiveness of datasharing,

498
00:32:32.934 --> 00:32:34.934
integration activities, linking
projects within the center,

499
00:32:34.934 --> 00:32:39.934
the effectiveness of research
translation engines Emily
projects to stakeholders,

500
00:32:39.934 --> 00:32:44.934
the appropriateness of community
engagement and training
activities,

501
00:32:44.934 --> 00:32:49.934
discussion of projects should be
continued, modified or

502
00:32:49.934 --> 00:32:53.934
discontinued. And strategies for
making changes to the project.

503
00:32:53.934 --> 00:32:57.934
The composition of the external
advisory committee should
reflect

504
00:32:57.934 --> 00:33:02.934
the goals of the center,
including appropriate scientific
expertise

505
00:33:02.934 --> 00:33:08.934
and appropriate stakeholders,
including represented from the
EPA,

506
00:33:08.934 --> 00:33:12.934
industry and/or community
organization for example

507
00:33:12.934 --> 00:33:19.000
all applicants should list
expertise of potential EAC
members, new

508
00:33:19.000 --> 00:33:23.934
applicants should not list names
of anticipated EAC members
unless

509
00:33:23.934 --> 00:33:27.934
they provide input into the
design of the application.

510
00:33:27.934 --> 00:33:29.934
>> Finally I want to mention the
budget

511
00:33:29.934 --> 00:33:35.934
for the administrative core is
not to exceed $150.000

512
00:33:35.934 --> 00:33:38.934
direct cost the center director
must commit

513
00:33:38.934 --> 00:33:41.934
a minimum of 1.8 persons month.

514
00:33:41.934 --> 00:33:45.934
>> The

515
00:33:45.934 --> 00:33:49.934
P 42 application is also
required to include a research
experience

516
00:33:49.934 --> 00:33:52.934
and training coordination core.

517
00:33:52.934 --> 00:33:57.934
RET cc. To coordinate graduate
and post doctrinal levels

518
00:33:57.934 --> 00:34:00.934
across as of winery research
experience, and

519
00:34:00.934 --> 00:34:04.934
training in fields related to
biomedical research, and
environmental

520
00:34:04.934 --> 00:34:07.934
science and engineering
research.

521
00:34:07.934 --> 00:34:11.934
This was called the training
Corps the name has been changed
to reflect

522
00:34:11.934 --> 00:34:17.000
the purpose of the core please
recall, the SRP defines

523
00:34:17.000 --> 00:34:21.000
trainees as graduate students,
and post the real researches,

524
00:34:21.000 --> 00:34:25.934
performing research and actively
supported by the Senate. While
undergraduates

525
00:34:25.934 --> 00:34:30.934
are recognized as are the
research continuing, and allowed
to participate

526
00:34:30.934 --> 00:34:33.934
in the court it is, the court
should direct its opportunities

527
00:34:33.934 --> 00:34:38.934
to the centers graduate and post
doctoral trainings. The core
should

528
00:34:38.934 --> 00:34:43.934
be designated to and designed to
promote interactions between the

529
00:34:43.934 --> 00:34:46.934
biomedical and environmental
science and engineering
trainings.

530
00:34:46.934 --> 00:34:50.934
Issue provide opportunities to
enhance the professional career
development,

531
00:34:50.934 --> 00:34:54.934
Courtney opportunities for
training participation in the
community engagement

532
00:34:54.934 --> 00:34:58.934
core, and administrative core
research translation function.

533
00:34:58.934 --> 00:35:02.934
Please note it is not mandatory
for trainings to participate in

534
00:35:02.934 --> 00:35:06.934
the community engagement, and
the ministry of translation

535
00:35:06.934 --> 00:35:09.934
function, but is highly
encourage.

536
00:35:09.934 --> 00:35:12.934
>> Also be asked to promote
training

537
00:35:12.934 --> 00:35:17.000
interaction with the data
management and analysis core.
And provide information

538
00:35:17.000 --> 00:35:22.000
about this and is the and
trainings to the SRP. The

539
00:35:22.000 --> 00:35:24.934
core she also described the
activities and training
opportunities

540
00:35:24.934 --> 00:35:29.934
for the center trainings, which
may include tell it curriculum

541
00:35:29.934 --> 00:35:34.934
only, selective course work to
for further requirement,

542
00:35:34.934 --> 00:35:39.934
cross disciplinary laboratory
experiences, women are

543
00:35:39.934 --> 00:35:42.934
serious, workshop conferences,
related to professional
development and

544
00:35:42.934 --> 00:35:46.934
travel to scientific meetings,
for example. It should also
provide

545
00:35:46.934 --> 00:35:51.934
a description of how the
training activities will be
daddy, and

546
00:35:51.934 --> 00:35:55.934
how trainee performance will be
monitored. It should also
indicate

547
00:35:55.934 --> 00:35:58.934
it's use of the NIH CareerTrac
database.

548
00:35:58.934 --> 00:36:04.934
That RET cc, training course
should also provide

549
00:36:04.934 --> 00:36:07.934
-- RETCC.

550
00:36:07.934 --> 00:36:12.934
Student postop alumni network,
or leadership

551
00:36:12.934 --> 00:36:19.000
committee conference calls. For
example, the

552
00:36:19.000 --> 00:36:24.000
RETCC, ladies and representative
graduate students

553
00:36:24.000 --> 00:36:29.000
and postop. And we have a link
for you to look at.

554
00:36:29.000 --> 00:36:31.000
>> Keep in mind that for the
renewal

555
00:36:31.000 --> 00:36:36.000
application, inquiring reviewers
want to know past training
successes,

556
00:36:36.000 --> 00:36:40.000
this could be included in the
training that is required in

557
00:36:40.000 --> 00:36:43.000
the tran 20.

558
00:36:43.000 --> 00:36:48.000
>> SRP centers may choose to
include

559
00:36:48.000 --> 00:36:52.000
a research support core,
[ Indiscernible ] providing
essential centralized

560
00:36:52.000 --> 00:36:57.000
services and resources that will
result in a and economy of

561
00:36:57.000 --> 00:37:01.000
effort and savings to the
overall cost of the center. They
can serve

562
00:37:01.000 --> 00:37:06.000
as a useful tool with
activities, integration of the
centers project

563
00:37:06.000 --> 00:37:08.000
in core.

564
00:37:08.000 --> 00:37:12.000
When proposed by a center, a
research support core must
support at least

565
00:37:12.000 --> 00:37:15.000
two or more research project.

566
00:37:15.000 --> 00:37:19.000
Typical core studies include
laboratory facilities,
analytical

567
00:37:19.000 --> 00:37:24.934
equipment and analytical
services. A research

568
00:37:24.934 --> 00:37:28.934
support core is principally, it
is designed as a service or

569
00:37:28.934 --> 00:37:33.934
a resource component, and highly
unusual to include research and

570
00:37:33.934 --> 00:37:36.934
research support.

571
00:37:36.934 --> 00:37:41.934
A possible exception would be
methodology development. In
addition

572
00:37:41.934 --> 00:37:45.934
to the description of the core,
you will see specific details
about

573
00:37:45.934 --> 00:37:49.934
this description and RFA. It
should include how the

574
00:37:49.934 --> 00:37:52.934
core will be used as a resource
to a center as a whole, discuss

575
00:37:52.934 --> 00:37:56.934
ways in which the center
centralized services will
produce an economy

576
00:37:56.934 --> 00:38:00.934
or effort and savings and
overall cost, compared to the
inclusion

577
00:38:00.934 --> 00:38:03.934
as a of each project in the
center.

578
00:38:03.934 --> 00:38:06.934
Research support core that
provide analytical and
quantitative services

579
00:38:06.934 --> 00:38:14.000
to the applicant Senokot
including quality assurance
section. -- Including.

580
00:38:14.000 --> 00:38:20.000
Implementing and assessing the
effectiveness of the quality
assurance

581
00:38:20.000 --> 00:38:23.934
and quality control operation,
and the status can be found

582
00:38:23.934 --> 00:38:26.934
at the URL provided on the
slide.

583
00:38:26.934 --> 00:38:30.934
>> Be certain to reference the
relevant table of supporting

584
00:38:30.934 --> 00:38:36.934
data managed in an announcement
-- analysis core.

585
00:38:36.934 --> 00:38:40.934
And for those projects that use
the core. The data

586
00:38:40.934 --> 00:38:45.934
will be managed and selected,
back up and related,
transferred, stored,

587
00:38:45.934 --> 00:38:48.934
documented and shared as
appropriate.

588
00:38:48.934 --> 00:38:51.934
Coordinated with the DMAC.

589
00:38:51.934 --> 00:38:56.934
>> I would like to also mention
pros and cons. On one

590
00:38:56.934 --> 00:39:00.934
hand they provide excellent
interaction and integration for
the assurance

591
00:39:00.934 --> 00:39:03.934
of quality.

592
00:39:03.934 --> 00:39:05.934
Some of the concert may not be
critical if the University
already

593
00:39:05.934 --> 00:39:09.934
has available facilities that
can be utilized, keep in mind an

594
00:39:09.934 --> 00:39:15.000
applicant needs to stay at the
11 component limit the
application.

595
00:39:15.000 --> 00:39:21.000
>> Since the research support is
optional, they do not

596
00:39:21.000 --> 00:39:23.000
have a set budget. I will now
pass it to Brittany Trottier,

597
00:39:23.000 --> 00:39:25.934
Health Specialist.

598
00:39:25.934 --> 00:39:30.934
>> Thank you Michelle. Now onto
the community engagement core

599
00:39:30.934 --> 00:39:33.968
which is required it is to

600
00:39:33.968 --> 00:39:38.934
ensure bidirectional
communication between

601
00:39:38.934 --> 00:39:42.934
the CDC and the community.

602
00:39:42.934 --> 00:39:43.601
Direct best practices and

603
00:39:43.601 --> 00:39:44.934
activities in community
engagement for prevention

604
00:39:44.934 --> 00:39:50.934
and/or intervention provide
potential solutions to
communities to the

605
00:39:50.934 --> 00:39:55.934
-- to reduce or mitigate the
impact of hazardous substances

606
00:39:55.934 --> 00:39:59.934
exposure.

607
00:39:59.934 --> 00:40:02.934
The exposure prevention and
intervention, empowers impacted
communities to

608
00:40:02.934 --> 00:40:07.934
be full participants and to
reduce the amount of toxicity,

609
00:40:07.934 --> 00:40:12.934
whether within home, school,
community, and environment. The
activities

610
00:40:12.934 --> 00:40:19.000
should complement the research
strength and problem solving
goals.

611
00:40:19.000 --> 00:40:23.000
It should also give a clear
indication about which community

612
00:40:23.000 --> 00:40:24.934
or communities that are planned
for partnerships, as

613
00:40:24.934 --> 00:40:28.934
well as which hazardous
substance will be impact.
Applicant should

614
00:40:28.934 --> 00:40:30.934
highlight the activity and
innovative plan for

615
00:40:30.934 --> 00:40:36.934
engaging the community, and
appropriate intervention and
prevention activities

616
00:40:36.934 --> 00:40:40.934
with communities. Complementing
the center's research.

617
00:40:40.934 --> 00:40:43.934
The C&C may work in partnership
with the community, or community

618
00:40:43.934 --> 00:40:48.934
serving organization, local
government groups, travel
counsel, community

619
00:40:48.934 --> 00:40:53.934
service groups, or
nongovernmental organizations
working

620
00:40:53.934 --> 00:40:57.934
closely with the community. In
addition, they may propose the
development

621
00:40:57.934 --> 00:41:03.934
of prevention of
[ Indiscernible ] economically
disadvantaged communities.

622
00:41:03.934 --> 00:41:07.934
These groups are frequently
impacted by exposure.

623
00:41:07.934 --> 00:41:11.934
It should be designed to have
the [ Indiscernible ]

624
00:41:11.934 --> 00:41:16.000
including a timeline not to
overlap with the study timeline,
and act

625
00:41:16.000 --> 00:41:22.000
to be's with milestone. Two
verifying -- of

626
00:41:22.000 --> 00:41:26.934
-- and approach to have sample
collection. Biological

627
00:41:26.934 --> 00:41:32.934
monitoring, and environmental
media to have

628
00:41:32.934 --> 00:41:38.934
directional exchange of needs
and recommendations of results.

629
00:41:38.934 --> 00:41:42.934
A point of contact should be
indicated with

630
00:41:42.934 --> 00:41:48.934
the strategy section.

631
00:41:48.934 --> 00:41:53.934
Appropriate activity for the C&C
mate include capacity building,

632
00:41:53.934 --> 00:41:58.934
tools and resources, knowledge
of exposure in the target

633
00:41:58.934 --> 00:42:02.934
community. In some cases, it may
not be required to include
biological

634
00:42:02.934 --> 00:42:05.934
or environmental sample
connection.

635
00:42:05.934 --> 00:42:08.934
-- CEC.

636
00:42:08.934 --> 00:42:12.934
I would like to emphasize that
the CEC proposing

637
00:42:12.934 --> 00:42:15.000
to collect samples, they should
include details of

638
00:42:15.000 --> 00:42:20.000
sampling methodology, analysis,
statistical calculation to
ensure

639
00:42:20.000 --> 00:42:25.934
the best practices are being
adopted and receiving

640
00:42:25.934 --> 00:42:28.934
scientific data.

641
00:42:28.934 --> 00:42:32.934
It has been listed in the
activity document on the

642
00:42:32.934 --> 00:42:35.934
website on the bottom right-hand
corner.

643
00:42:35.934 --> 00:42:38.934
>> I will pass it back over to
Michelle.

644
00:42:38.934 --> 00:42:41.934
>> Thank you.

645
00:42:41.934 --> 00:42:45.934
I will tell you about that data
management and analysis

646
00:42:45.934 --> 00:42:50.934
core. Due to time we can only
cover major highlights however
it

647
00:42:50.934 --> 00:42:55.934
has detailed information about
the core. Since

648
00:42:55.934 --> 00:42:58.934
this is new, it is important
that you read the RSA carefully.
Here

649
00:42:58.934 --> 00:43:04.934
are the highlights. We created
it because SRP the acknowledges

650
00:43:04.934 --> 00:43:07.934
management and integration of
data is critical to understand
and

651
00:43:07.934 --> 00:43:14.000
breaking the link between
exposure and deli. --

652
00:43:14.000 --> 00:43:19.000
[ Indiscernible ]. Established
coordination and monitor
processes

653
00:43:19.000 --> 00:43:23.000
for data analysis.

654
00:43:23.000 --> 00:43:24.934
Work with the project core
leaders to ensure high data the
quality

655
00:43:24.934 --> 00:43:29.934
through lifecycle of data. It
should support and facilitate
the management

656
00:43:29.934 --> 00:43:35.934
of data, irrespective of data
sets. It should establish,

657
00:43:35.934 --> 00:43:39.934
coordinate and monitor processes
for analysis, working

658
00:43:39.934 --> 00:43:42.934
closely with project and core
leaders to ensure high quality
data

659
00:43:42.934 --> 00:43:46.934
through the entire lifecycle of
the data.

660
00:43:46.934 --> 00:43:50.934
It also has a coordinating role
to work with Dr. core leaders,
to

661
00:43:50.934 --> 00:43:55.934
identify opportunities for
integrating project in court
generated data,

662
00:43:55.934 --> 00:43:58.934
with other existing datasets.

663
00:43:58.934 --> 00:44:04.934
In addition, the DMAC should
have data between my medical

664
00:44:04.934 --> 00:44:08.934
and environmental science that
accelerating the impact of this

665
00:44:08.934 --> 00:44:14.000
and his research. The core
should outline specific object

666
00:44:14.000 --> 00:44:20.000
of singles and comprehension of
data management including,

667
00:44:20.000 --> 00:44:25.934
coordination with project and
course, fostering datasharing
and

668
00:44:25.934 --> 00:44:29.934
interoperability, and data
quality assurance and quality

669
00:44:29.934 --> 00:44:32.934
control it should contain a
brief statement of how the court
integrates

670
00:44:32.934 --> 00:44:38.934
with each of the research
projects and course, and how it
helps to

671
00:44:38.934 --> 00:44:39.934
achieve center goals.

672
00:44:39.934 --> 00:44:44.934
And it may also include
additional functionalities such
as

673
00:44:44.934 --> 00:44:48.934
biostatistics, bioinformatics,
geographical information
systems,

674
00:44:48.934 --> 00:44:53.934
and computational modeling, and
these additional functionalities

675
00:44:53.934 --> 00:44:57.934
would be optional. It should not
detract from the data

676
00:44:57.934 --> 00:45:00.934
management and data management
responsibilities.

677
00:45:00.934 --> 00:45:03.934
What is not expected for the
Janice Allen, Scientific Review

678
00:45:03.934 --> 00:45:07.934
Officer to have the sentence
data, it should be familiar with
databases

679
00:45:07.934 --> 00:45:10.934
that can be used to deposit the
data, and develop a plan for
project

680
00:45:10.934 --> 00:45:16.000
and core members, to have access
and use the data

681
00:45:16.000 --> 00:45:21.000
generated from the center with
appropriate, ethical and
control.

682
00:45:21.000 --> 00:45:24.934
In addition, it should designate
a point of contact to inform SRP

683
00:45:24.934 --> 00:45:28.934
staff, dataset deposition could
be optional, SRP

684
00:45:28.934 --> 00:45:30.934
data collection tool.

685
00:45:30.934 --> 00:45:35.934
And provide a point of contact
for the regular SRP research
translation,

686
00:45:35.934 --> 00:45:39.934
community engagement, data
management and analysis core
conference call.

687
00:45:39.934 --> 00:45:43.934
I also want to mention this is
the first P 42 RFA

688
00:45:43.934 --> 00:45:49.934
with a DMAC requirement. Renewal
applications have a research

689
00:45:49.934 --> 00:45:55.934
support core that
[ Indiscernible ] and other

690
00:45:55.934 --> 00:45:56.934
DMAC activities.

691
00:45:56.934 --> 00:46:02.934
It is permissible to include as
a part of the DMAC, a summary

692
00:46:02.934 --> 00:46:05.934
of act Tibbett is carried out
during the performance period.
Including

693
00:46:05.934 --> 00:46:10.934
information on utilization by
the individual project and core.

694
00:46:10.934 --> 00:46:16.000
For renewal applications without
previous DMAC,

695
00:46:16.000 --> 00:46:18.000
this section is not applicable.

696
00:46:18.000 --> 00:46:23.067
You will see we have provided
similar datasharing policies

697
00:46:23.067 --> 00:46:28.000
and resources. Highly encouraged
to review those as we put this
together.

698
00:46:28.000 --> 00:46:33.000
>> To summarize, as

699
00:46:33.000 --> 00:46:36.000
you can imagine there are many
parts to a center. To be

700
00:46:36.000 --> 00:46:41.000
successful, projects and course
need to be uniformly
meritorious,

701
00:46:41.000 --> 00:46:47.000
demonstrating interaction,
addressing major problems, and
having

702
00:46:47.000 --> 00:46:52.000
effective decision-making.

703
00:46:52.000 --> 00:46:54.000
If you are interested in
developing an application, do
not hesitate

704
00:46:54.000 --> 00:46:59.000
to contact SRP staff member we
are here to help.

705
00:46:59.000 --> 00:47:01.000
I will turn the presentation
open to Janice Allen, Scientific
Review

706
00:47:01.000 --> 00:47:04.000
Officer.

707
00:47:04.000 --> 00:47:07.000
>> Thank you.

708
00:47:07.000 --> 00:47:11.000
I want to tell you that others

709
00:47:11.000 --> 00:47:20.000
in the room, a part
of the review group, are
[ Indiscernible ].

710
00:47:20.000 --> 00:47:25.934
We have Deborah Jones,

711
00:47:25.934 --> 00:47:31.934
who is a friend also. And we
have the primary

712
00:47:31.934 --> 00:47:37.934
SRO from last year, and
graciously agreed to be here
today,

713
00:47:37.934 --> 00:47:43.934
in case we have any questions
that may come up or reflect

714
00:47:43.934 --> 00:47:48.934
review issues. And many of you
may have already seen these

715
00:47:48.934 --> 00:47:51.934
slides, I have modified the
slides she presented last year
with

716
00:47:51.934 --> 00:47:54.934
some updates.

717
00:47:54.934 --> 00:47:59.934
>> If we could go to the. This
is

718
00:47:59.934 --> 00:48:05.934
pretty much the same for the
review process -- for all

719
00:48:05.934 --> 00:48:10.934
application mechanisms. Here we
have with the dates,

720
00:48:10.934 --> 00:48:17.000
you are encouraged to submit a
letter of intent. And we will go

721
00:48:17.000 --> 00:48:23.000
over that in a bit what I would
like to see. That is

722
00:48:23.000 --> 00:48:28.934
November 19. One month later,
your Apple nations will be

723
00:48:28.934 --> 00:48:31.934
due. As soon as we get those, it
takes about one week

724
00:48:31.934 --> 00:48:36.934
at the ends to to get the
applications online. We would do

725
00:48:36.934 --> 00:48:42.934
an administrative review, which
will designate whether

726
00:48:42.934 --> 00:48:48.934
your application is responsive
or nonresponsive. This is an
area

727
00:48:48.934 --> 00:48:54.934
that is important for you to
contact your Superfund staff

728
00:48:54.934 --> 00:49:00.934
because this should not be a
reason for them to
scientifically

729
00:49:00.934 --> 00:49:06.934
nonresponsive. There are also
technicalities, that might

730
00:49:06.934 --> 00:49:09.934
designate this as well.

731
00:49:09.934 --> 00:49:16.000
But again, staff is here to give
guidance on this information.

732
00:49:16.000 --> 00:49:22.000
>> The review committee is
formed, and many have served

733
00:49:22.000 --> 00:49:25.934
on NIEHS.

734
00:49:25.934 --> 00:49:31.934
The reviewers have the expertise
to review your

735
00:49:31.934 --> 00:49:37.934
application. And these people
come from all over the U. S..

736
00:49:37.934 --> 00:49:40.934
Primarily universities.

737
00:49:40.934 --> 00:49:45.934
We have a good representation --

738
00:49:45.934 --> 00:49:51.934
the geographic areas within the
country, as well as
underrepresented

739
00:49:51.934 --> 00:49:53.934
minorities.

740
00:49:53.934 --> 00:49:57.934
They will have experience in
reviewing applications.

741
00:49:57.934 --> 00:50:02.934
>> This will take up most of the
time that we have for

742
00:50:02.934 --> 00:50:08.934
establishing the review meeting,
which will be held sometime

743
00:50:08.934 --> 00:50:12.934
May of next year. As you
probably also

744
00:50:12.934 --> 00:50:18.000
are aware, the review committee
determines whether or not your
application

745
00:50:18.000 --> 00:50:23.000
is discussed or not discussed.
In most cases you will get a
summary

746
00:50:23.000 --> 00:50:28.934
statement from the reviewers
with expertise needed,

747
00:50:28.934 --> 00:50:32.934
to review your application. In
the non-discussed applications,

748
00:50:32.934 --> 00:50:36.934
you will not get a summary
and/or a

749
00:50:36.934 --> 00:50:42.934
resume of the summary discussion
at the review meeting itself.

750
00:50:42.934 --> 00:50:47.934
>> Is applications will go to
our counsel,

751
00:50:47.934 --> 00:50:53.934
and funding decisions will be
made after that.

752
00:50:53.934 --> 00:50:59.934
>> Before you submit your

753
00:50:59.934 --> 00:51:03.934
P 42 application, you want to
make sure you are in

754
00:51:03.934 --> 00:51:09.934
contact with the NIEHS staff.
Discuss your application

755
00:51:09.934 --> 00:51:16.000
with them. And the letter of
intent is very

756
00:51:16.000 --> 00:51:19.000
important to review.

757
00:51:19.000 --> 00:51:24.934
We use this to start recruiting
reviewers.

758
00:51:24.934 --> 00:51:29.934
It does not require -- it is
extremely helpful

759
00:51:29.934 --> 00:51:32.934
to us.

760
00:51:32.934 --> 00:51:37.934
Listed on the slide, items you
might include in the letter of
intent.

761
00:51:37.934 --> 00:51:43.934
Some send abstract or specific
pages that

762
00:51:43.934 --> 00:51:48.934
[ Indiscernible ]. And when you
send us it is not binding.

763
00:51:48.934 --> 00:51:53.934
Within the next month after
this, you may decide a different

764
00:51:53.934 --> 00:51:56.934
emphasis in a project or a core.

765
00:51:56.934 --> 00:52:02.934
Again, we won a general idea of
what kinds of reviewers

766
00:52:02.934 --> 00:52:05.934
are needed to start recruiting.

767
00:52:05.934 --> 00:52:11.934
>> Also I will mention this,
this is a

768
00:52:11.934 --> 00:52:15.000
clinical trial optional.

769
00:52:15.000 --> 00:52:21.000
It would be nice if you could
include --

770
00:52:21.000 --> 00:52:26.934
if you are going to exercise
that option. If you are

771
00:52:26.934 --> 00:52:32.934
new to submitting, as Michelle
stated, we do

772
00:52:32.934 --> 00:52:33.934
not want you to submit names.

773
00:52:33.934 --> 00:52:39.934
Or potential advisory committee
members. Unless they have been

774
00:52:39.934 --> 00:52:41.934
involved up to that point.

775
00:52:41.934 --> 00:52:47.934
In the preparation of your
application -- adding names

776
00:52:47.934 --> 00:52:53.934
will limit our pool of reviewer
because of conflict.

777
00:52:53.934 --> 00:52:59.934
We would like you to list the
expertise that you are

778
00:52:59.934 --> 00:53:02.934
planning on using in recruiting.

779
00:53:02.934 --> 00:53:07.934
>> This is an overview of the
here

780
00:53:07.934 --> 00:53:14.000
review process. -- Here. -- Peer
review.

781
00:53:14.000 --> 00:53:20.000
We have references as well
listed

782
00:53:20.000 --> 00:53:25.934
for you. We will review the
individual research projects.

783
00:53:25.934 --> 00:53:30.934
And importantly, the review of
the overall center.

784
00:53:30.934 --> 00:53:36.934
Each project core will receive a
score. You will also

785
00:53:36.934 --> 00:53:41.934
receive an overview. So you
understand, as mentioned, to

786
00:53:41.934 --> 00:53:47.934
be able to be sure to submit

787
00:53:47.934 --> 00:53:50.934
[ Indiscernible ] and projects.

788
00:53:50.934 --> 00:53:55.934
These are all going to be
reviewed. On the next

789
00:53:55.934 --> 00:54:01.934
slide, I will not go into
detail. Most of you can probably

790
00:54:01.934 --> 00:54:07.934
state this better than I. We
have the five criteria in

791
00:54:07.934 --> 00:54:14.000
reviewing. Submitted
applications, we have five
listed. We

792
00:54:14.000 --> 00:54:20.000
score them from one

793
00:54:20.000 --> 00:54:25.934
being the best and nine being
the worst. I do not like to

794
00:54:25.934 --> 00:54:30.934
use that word. Also we have two
other criteria,

795
00:54:30.934 --> 00:54:33.934
contribution to the center as a
whole, and other specific
criteria

796
00:54:33.934 --> 00:54:39.934
that go into the overall scoring
of your application, such as
human

797
00:54:39.934 --> 00:54:47.934
subject, animal care, and
biohazard. And

798
00:54:47.934 --> 00:54:52.934
they are not considered in the
score. Each project that is
reviewed,

799
00:54:52.934 --> 00:54:57.934
it will receive a score, unless
the application is not
discussed,

800
00:54:57.934 --> 00:55:03.934
at which point they will not
receive a summary,

801
00:55:03.934 --> 00:55:06.934
or a score.

802
00:55:06.934 --> 00:55:12.934
>> Next, within the core,

803
00:55:12.934 --> 00:55:16.000
we have an overarching theme.

804
00:55:16.000 --> 00:55:20.000
And feet integration,
collaboration and's energy of
all

805
00:55:20.000 --> 00:55:26.934
your projects and cores are
essential for a good scoring
application.

806
00:55:26.934 --> 00:55:30.934
We will evaluate each score of
the core.

807
00:55:30.934 --> 00:55:35.934
Again, refer to your RSA for

808
00:55:35.934 --> 00:55:38.934
specific criteria.

809
00:55:38.934 --> 00:55:43.934
>> Let's break down individually
for a moment,

810
00:55:43.934 --> 00:55:48.934
the overall center. You want
your overall center to address

811
00:55:48.934 --> 00:55:53.934
a critical problem relevant to
the SRP. Relevant to

812
00:55:53.934 --> 00:56:02.934
merit of projects and cores,
scientific gain.

813
00:56:02.934 --> 00:56:07.934
Again, mentioning integration,
century

814
00:56:07.934 --> 00:56:14.000
and collaboration of each of
these entities --'s energy. And

815
00:56:14.000 --> 00:56:18.000
of course, leadership. --'s
energy.

816
00:56:18.000 --> 00:56:24.000
>> We want to make sure that the
reviewers will evaluate

817
00:56:24.000 --> 00:56:30.000
you. We have a list of helpful
hints.

818
00:56:30.000 --> 00:56:34.000
You want to read and understand
the

819
00:56:34.000 --> 00:56:36.000
RSA. Reviewers will do this.

820
00:56:36.000 --> 00:56:41.000
They will be instructed to read
the RSA, and

821
00:56:41.000 --> 00:56:47.000
they will know what you should
put in there.

822
00:56:47.000 --> 00:56:53.000
If you leave out something they
will ding you for. Again,

823
00:56:53.000 --> 00:56:58.000
contact program staff for
clarification of scientific
matters.

824
00:56:58.000 --> 00:57:04.000
Following guidelines, page
limits, font size, and

825
00:57:04.000 --> 00:57:07.000
so forth. You really do not want
to think about that, but it

826
00:57:07.000 --> 00:57:10.000
does not contribute to the font.

827
00:57:10.000 --> 00:57:16.000
But we as -- we need to pay
attention to

828
00:57:16.000 --> 00:57:20.000
that. Applications may be sent
back for these reasons.

829
00:57:20.000 --> 00:57:25.934
If you have any questions about
any of this, our

830
00:57:25.934 --> 00:57:30.934
you can contact is a -- contact
us

831
00:57:30.934 --> 00:57:33.934
by email and we will answer your
questions.

832
00:57:33.934 --> 00:57:39.934
>> It does not matter if it is a
[ Indiscernible ] application,

833
00:57:39.934 --> 00:57:44.934
you want to make sure you submit
early. You want to start

834
00:57:44.934 --> 00:57:49.934
the process early. And probably
many of you have already done
this.

835
00:57:49.934 --> 00:57:55.934
I like to tell people, inform
your grant office,

836
00:57:55.934 --> 00:58:01.934
and that you are in the process
of doing this. Have them

837
00:58:01.934 --> 00:58:06.934
keep time for you so they can
submit for you without any
delay.

838
00:58:06.934 --> 00:58:12.934
People sometimes feel, I can
submit the day before, that

839
00:58:12.934 --> 00:58:17.000
would give me a day to take care
of any errors,

840
00:58:17.000 --> 00:58:22.000
that should be okay. I cannot
tell you, I have had to send
back applications,

841
00:58:22.000 --> 00:58:27.934
and I would love everyone
[ Indiscernible ], but I am told
that

842
00:58:27.934 --> 00:58:32.934
if errors you correct -- some of
those do

843
00:58:32.934 --> 00:58:37.934
not get loaded into the system
until the day after. And
considered late

844
00:58:37.934 --> 00:58:42.934
at that point. There is nothing
any of us can do for you at that

845
00:58:42.934 --> 00:58:45.934
point. Please start early.

846
00:58:45.934 --> 00:58:51.934
Also, if you go in after your
submission

847
00:58:51.934 --> 00:58:56.934
and you feel everything is okay,
[ Indiscernible ]. Make sure all

848
00:58:56.934 --> 00:59:02.934
components are there. If you
cannot see what should be there,
I

849
00:59:02.934 --> 00:59:05.934
cannot see what should be there.

850
00:59:05.934 --> 00:59:11.934
Therefore, if sections are
missing, your application may

851
00:59:11.934 --> 00:59:17.000
be returned. These are just a
group -- [ Indiscernible ].

852
00:59:17.000 --> 00:59:21.000
>> We have some grantsmanship
issues. Be clear and

853
00:59:21.000 --> 00:59:26.934
concise. Don't expect reviewers
to know what you mean. All
components

854
00:59:26.934 --> 00:59:29.934
are important.

855
00:59:29.934 --> 00:59:35.934
One week research project will
impact the entire overall score.

856
00:59:35.934 --> 00:59:41.934
Also, the clear and concise in
your

857
00:59:41.934 --> 00:59:47.934
writeups, and if you ramble,
that will

858
00:59:47.934 --> 00:59:53.934
reduce the cohesiveness of the
center. And you can be gained
for

859
00:59:53.934 --> 00:59:57.934
that. Too many objects will
sometimes make your application

860
00:59:57.934 --> 01:00:00.934
sink under its own weight.

861
01:00:00.934 --> 01:00:05.934
Again, start early. That

862
01:00:05.934 --> 01:00:11.934
will give you time to collect
any problems that you may have.

863
01:00:11.934 --> 01:00:17.000
>> I just want to show you some
resources for the webpage.

864
01:00:17.000 --> 01:00:23.000
It is extremely important -- you
should look at it.

865
01:00:23.000 --> 01:00:28.934
And while doing this, there is a
link that

866
01:00:28.934 --> 01:00:34.934
will be -- and FAQ section. As
we get questions

867
01:00:34.934 --> 01:00:37.934
we will up date the FAQs.

868
01:00:37.934 --> 01:00:43.934
And it will include any
concerns.

869
01:00:43.934 --> 01:00:47.934
If you have a question, someone
may have one as well and we want

870
01:00:47.934 --> 01:00:50.934
to be fair across the board.

871
01:00:50.934 --> 01:00:56.934
>> I will also say, within that
FAQ,

872
01:00:56.934 --> 01:00:59.934
I do not think about this until
a few minutes

873
01:00:59.934 --> 01:01:05.934
before this, I will give you
some guidance on this new

874
01:01:05.934 --> 01:01:07.934
clinical trial aspect.

875
01:01:07.934 --> 01:01:12.934
Again, if you could include in
your LOI,

876
01:01:12.934 --> 01:01:19.000
you can activate the option. Let
me know.

877
01:01:19.000 --> 01:01:23.000
Also in the FAQ, we will have a
section or clinical trial
optional

878
01:01:23.000 --> 01:01:25.934
guidelines.

879
01:01:25.934 --> 01:01:31.934
>> The last slide -- please pay
attention to

880
01:01:31.934 --> 01:01:33.934
the slide.

881
01:01:33.934 --> 01:01:36.934
This is not new to you, but a
lot of people contact me and
asked where

882
01:01:36.934 --> 01:01:42.934
should I put the scientific
premise or scientific rigor.
This

883
01:01:42.934 --> 01:01:45.934
tells you where you should go.

884
01:01:45.934 --> 01:01:50.934
Some people may make a separate
section with an appropriate
heading,

885
01:01:50.934 --> 01:01:56.934
but a lot of people will just
[ Indiscernible ]

886
01:01:56.934 --> 01:02:02.934
for the scientific premise, you
may have bold

887
01:02:02.934 --> 01:02:07.934
address. That would be fine.

888
01:02:07.934 --> 01:02:14.000
You want to make the reviewers
not have to hunt and insert

889
01:02:14.000 --> 01:02:19.000
-- search for your application.
Mold lettering is good

890
01:02:19.000 --> 01:02:24.934
-- bold. We just do not want you
to

891
01:02:24.934 --> 01:02:27.934
miss out. And not have it
identified for the

892
01:02:27.934 --> 01:02:30.934
reviewer.

893
01:02:30.934 --> 01:02:34.934
>> The next few slides, if

894
01:02:34.934 --> 01:02:37.934
you can just pass through those.

895
01:02:37.934 --> 01:02:43.934
It will give you more guidance
as scientific premise,

896
01:02:43.934 --> 01:02:48.934
regular, and biological
[ Indiscernible ]

897
01:02:48.934 --> 01:02:51.934
authentication of chemical
resources.

898
01:02:51.934 --> 01:02:56.934
These are items reviewers will
be looking for.

899
01:02:56.934 --> 01:03:02.934
>> Make sure that you know what
to include.

900
01:03:02.934 --> 01:03:08.934
The last slide have phone
numbers and emails for each

901
01:03:08.934 --> 01:03:15.000
of us. Along with our review
team. You can

902
01:03:15.000 --> 01:03:21.000
contact any of us. I know how it
is to do something, and

903
01:03:21.000 --> 01:03:24.934
you want an answer right away.

904
01:03:24.934 --> 01:03:29.934
You may not be able to move
forward at that point mentally.
Be sure

905
01:03:29.934 --> 01:03:35.934
to call one of us. We will get
back to you as soon as

906
01:03:35.934 --> 01:03:39.934
possible. I must say, I am
looking forward to reading your

907
01:03:39.934 --> 01:03:44.934
applications. Please contact us
if you need any information.

908
01:03:44.934 --> 01:03:47.934
Thank you.

909
01:03:47.934 --> 01:03:51.934
>> My name is Lisa Edwards and I
will discuss

910
01:03:51.934 --> 01:03:54.934
your budget.

911
01:03:54.934 --> 01:04:00.934
>> As mentioned, you will

912
01:04:00.934 --> 01:04:03.934
use assist to submit your
application.

913
01:04:03.934 --> 01:04:09.934
This slide has links for the
multi-project grant.

914
01:04:09.934 --> 01:04:15.000
Use the SF or two for submission
of the budget.

915
01:04:15.000 --> 01:04:19.000
You must submit budget pages for
all project or and some

916
01:04:19.000 --> 01:04:22.000
awards.

917
01:04:22.000 --> 01:04:27.934
>> This page lists a link to

918
01:04:27.934 --> 01:04:30.934
the SF or two for budget pages.

919
01:04:30.934 --> 01:04:33.934
-- 424.

920
01:04:33.934 --> 01:04:39.934
Make sure that you are -- using

921
01:04:39.934 --> 01:04:42.934
the most current policy
statement.

922
01:04:42.934 --> 01:04:47.934
This is often updated on Tober
of every year.

923
01:04:47.934 --> 01:04:52.934
We will enter a new year in
October prior to the submission

924
01:04:52.934 --> 01:04:57.934
of your application. Make sure
you are using the current policy
statement.

925
01:04:57.934 --> 01:05:02.934
If your application sure is
[ Indiscernible ] you will

926
01:05:02.934 --> 01:05:10.934
be asked to submit your IRB
approval, and any

927
01:05:10.934 --> 01:05:14.000
other statement summary
concerns.

928
01:05:14.000 --> 01:05:20.000
>> Your budget should be
submitted

929
01:05:20.000 --> 01:05:23.000
as a detailed categorical
budget.

930
01:05:23.000 --> 01:05:27.934
As mentioned earlier, you must
submit a budget for each
project,

931
01:05:27.934 --> 01:05:30.934
each core and each sub award.

932
01:05:30.934 --> 01:05:34.934
I am sorry to keep repeating
this, we often get applications

933
01:05:34.934 --> 01:05:37.934
and the sub award budget is
missing.

934
01:05:37.934 --> 01:05:43.934
This will hold up an award if
you are [ Indiscernible ]. You
are

935
01:05:43.934 --> 01:05:48.934
allowed to request an
escalation, note no longer
allowing

936
01:05:48.934 --> 01:05:53.934
escalation. It will be removed
from your award before it

937
01:05:53.934 --> 01:05:58.934
is issued. To ensure that your
budget is not,, you should

938
01:05:58.934 --> 01:06:04.934
ensure that you provide a
justification for any cost this
week rested above

939
01:06:04.934 --> 01:06:10.934
what was requested within your
first year. Is a requirement of

940
01:06:10.934 --> 01:06:19.000
the program that you include a
travel and [ Indiscernible ] to

941
01:06:19.000 --> 01:06:22.000
attend the Superfund every year.

942
01:06:22.000 --> 01:06:28.000
>> This page gives more of the
same.

943
01:06:28.000 --> 01:06:33.000
I want to emphasize you must
submit budget pages for
projects,

944
01:06:33.000 --> 01:06:36.000
cores, and any sub award.

945
01:06:36.000 --> 01:06:41.000
You must submit justification of
cost. It

946
01:06:41.000 --> 01:06:45.000
is important that if you are
planning to have any type of

947
01:06:45.000 --> 01:06:51.000
changes in your outer ear, you
submit justification. And
anything

948
01:06:51.000 --> 01:06:56.000
that looks like an escalation,
it will be removed from the
application.

949
01:06:56.000 --> 01:07:01.000
>> The next slide will show
examples of the budget

950
01:07:01.000 --> 01:07:04.000
page and what it will look like.

951
01:07:04.000 --> 01:07:10.000
This page consist of your
personnel cost. Section

952
01:07:10.000 --> 01:07:13.000
A and the Mac.

953
01:07:13.000 --> 01:07:18.000
Senior key personnel -- B.

954
01:07:18.000 --> 01:07:23.934
>> The next page

955
01:07:23.934 --> 01:07:29.934
consist of your section C
through E.

956
01:07:29.934 --> 01:07:35.934
And section C is equipment,
section D

957
01:07:35.934 --> 01:07:41.934
was travel. Break domestic and
foreign travel. We do not

958
01:07:41.934 --> 01:07:44.934
use section in.

959
01:07:44.934 --> 01:07:47.934
-- E.

960
01:07:47.934 --> 01:07:56.934
>> Next please.

961
01:07:56.934 --> 01:08:01.934
Section F through K is where you
put the majority of

962
01:08:01.934 --> 01:08:07.934
your budget. This section will
include material, supply, your

963
01:08:07.934 --> 01:08:14.000
consortia cost, any types of
other cost. Also include

964
01:08:14.000 --> 01:08:18.000
your total direct cost. And your
cost will be broken out.

965
01:08:18.000 --> 01:08:22.000
>> You will also have a

966
01:08:22.000 --> 01:08:25.934
composite page, which will total
up all cost your project, and

967
01:08:25.934 --> 01:08:28.934
all of your core.

968
01:08:28.934 --> 01:08:37.934
>> The next gives you a list of
resources.

969
01:08:37.934 --> 01:08:40.934
These are resources that you can
refer to

970
01:08:40.934 --> 01:08:43.934
while you put your application
together.

971
01:08:43.934 --> 01:08:52.934
>> Okay, that is it.

972
01:08:52.934 --> 01:08:55.934
>> Thank you.

973
01:08:55.934 --> 01:09:01.934
Next slide.

974
01:09:01.934 --> 01:09:06.934
Go back one.

975
01:09:06.934 --> 01:09:11.934
First of all, thank you all for
your attention during this
funding

976
01:09:11.934 --> 01:09:17.000
opportunity. I want to leave you
with two thoughts at this point.

977
01:09:17.000 --> 01:09:22.000
This has been said before.

978
01:09:22.000 --> 01:09:27.934
The redundancy is an important
thing to have in the situation.
Submit

979
01:09:27.934 --> 01:09:33.934
early. You are given a window of
the days to correct any

980
01:09:33.934 --> 01:09:35.934
errors. If you wait until the
last minute you will lose the

981
01:09:35.934 --> 01:09:39.934
opportunity to correct errors,
and your application could get
rejected

982
01:09:39.934 --> 01:09:45.934
by the system that could have
been fixed in time.

983
01:09:45.934 --> 01:09:49.934
That is number 1. Secondly, we
are here to help you during

984
01:09:49.934 --> 01:09:53.934
the process. We encourage you to
reach out if

985
01:09:53.934 --> 01:09:59.934
you are contemplating submitting
an application. Especially if

986
01:09:59.934 --> 01:10:02.934
you have not already been in
touch with any of

987
01:10:02.934 --> 01:10:07.934
the folks here, listed on the
slide. In general, the program
officer

988
01:10:07.934 --> 01:10:11.934
listed include Danielle,
Michelle and Heather.

989
01:10:11.934 --> 01:10:18.000
Have a good first point of
contact, and can direct
questions to the

990
01:10:18.000 --> 01:10:23.000
right person. We are here to
help you. And please reach out.

991
01:10:23.000 --> 01:10:27.934
The important thing that I want
to say, we want to be able to
support

992
01:10:27.934 --> 01:10:33.934
the most meritorious science
that we possibly can.

993
01:10:33.934 --> 01:10:38.934
That requires a working
relationship as best as

994
01:10:38.934 --> 01:10:44.934
we can under the circumstances
of limitations within NIEHS.

995
01:10:44.934 --> 01:10:49.934
>> I like to thank you. If you
have any questions.

996
01:10:49.934 --> 01:10:55.934
-- I would like to acknowledge
those folks behind the scenes,
as

997
01:10:55.934 --> 01:11:01.934
they have made today's webinar
possible. Including,

998
01:11:01.934 --> 01:11:07.934
EPA -- thank you Jean. And Sarah
from

999
01:11:07.934 --> 01:11:09.934
MDB.

1000
01:11:09.934 --> 01:11:15.000
They have allowed us to go
through this entire process. I
realize we

1001
01:11:15.000 --> 01:11:19.000
have covered a lot, but at this
time we are open to questions.

1002
01:11:19.000 --> 01:11:22.000
I will turn it over to the
monetary.

1003
01:11:22.000 --> 01:11:24.934
-- Moderator.

1004
01:11:24.934 --> 01:11:28.934
>> You can also list your
questions

1005
01:11:28.934 --> 01:11:33.934
in the chat pot. The first
question -- can innovation

1006
01:11:33.934 --> 01:11:39.934
sections require for the
[ Indiscernible ] strategy
section?

1007
01:11:39.934 --> 01:11:45.934
>> This is Heather. I will

1008
01:11:45.934 --> 01:11:49.934
jump in because we have this
question before. And a lot of
the

1009
01:11:49.934 --> 01:11:54.934
course, there is not much
specificity on what goes into

1010
01:11:54.934 --> 01:12:00.934
section by section, unlike in
the project. We recommend a

1011
01:12:00.934 --> 01:12:05.934
-- research strategy pertaining
to your core.

1012
01:12:05.934 --> 01:12:10.934
Also look at the review criteria
for that

1013
01:12:10.934 --> 01:12:15.000
core, making sure you cover all
bases.

1014
01:12:15.000 --> 01:12:18.000
Of course you can include
significance and innovation, but
is not required

1015
01:12:18.000 --> 01:12:21.000
in the community engagement
core.

1016
01:12:21.000 --> 01:12:26.934
>> Our next question, is the

1017
01:12:26.934 --> 01:12:31.934
data core included in the direct
cost from administrative

1018
01:12:31.934 --> 01:12:35.934
research experience, training
coronation not exceeding 20% of

1019
01:12:35.934 --> 01:12:38.934
the caudal -- [ Indiscernible ]?

1020
01:12:38.934 --> 01:12:42.934
>> No. The DMAC is not

1021
01:12:42.934 --> 01:12:45.934
included.

1022
01:12:45.934 --> 01:12:51.934
>> Okay.

1023
01:12:51.934 --> 01:12:54.934
Is a resubmission application
included

1024
01:12:54.934 --> 01:13:00.934
in the statement that applicant
should not list names

1025
01:13:00.934 --> 01:13:02.934
of members unless they provide
input into the

1026
01:13:02.934 --> 01:13:05.934
design of the application?

1027
01:13:05.934 --> 01:13:10.934
>> If you resubmit, and you have
the committee already,

1028
01:13:10.934 --> 01:13:16.000
those names would be -- if you
use the same people --

1029
01:13:16.000 --> 01:13:17.000
those names would be listed.

1030
01:13:17.000 --> 01:13:21.000
If adding or deleting some
people at that point, you would
submit

1031
01:13:21.000 --> 01:13:24.934
the expertise needed, but not a
new name.

1032
01:13:24.934 --> 01:13:29.934
>> If this is not previously
funded application.

1033
01:13:29.934 --> 01:13:34.934
It is now but now for
resubmission.

1034
01:13:34.934 --> 01:13:40.934
>> Considering it new, and
unless those

1035
01:13:40.934 --> 01:13:45.934
-- if you continue with the

1036
01:13:45.934 --> 01:13:52.934
same members, again, do not list
names unless they helped

1037
01:13:52.934 --> 01:13:57.934
with preparation. We consider
them as new. And we

1038
01:13:57.934 --> 01:14:00.934
would like their expertise.

1039
01:14:00.934 --> 01:14:03.934
>> Thank you.

1040
01:14:03.934 --> 01:14:07.934
Does the 1.75 million direct
cost includes consortium,

1041
01:14:07.934 --> 01:14:11.934
or is it the lemon
[ Indiscernible - low volume ]?

1042
01:14:11.934 --> 01:14:18.000
>> It is less the consortia.

1043
01:14:18.000 --> 01:14:23.000
Please note when you put in your
application, when you come

1044
01:14:23.000 --> 01:14:25.934
up with your total direct cost,
that amount is included in your

1045
01:14:25.934 --> 01:14:30.934
total direct cost we only take
it out to look at your cat for
submission.

1046
01:14:30.934 --> 01:14:33.934
-- Cap.

1047
01:14:33.934 --> 01:14:36.934
>> [ Indiscernible ]

1048
01:14:36.934 --> 01:14:39.934
>> Yes, they are allowed.

1049
01:14:39.934 --> 01:14:43.934
>> Will die training Corps and
travel

1050
01:14:43.934 --> 01:14:49.934
beacons to a participant support
cost?

1051
01:14:49.934 --> 01:14:53.934
>> No. Not as a participant
cost.

1052
01:14:53.934 --> 01:14:58.934
>> Should the salary for
individuals above the

1053
01:14:58.934 --> 01:15:01.934
cat should be [ Indiscernible ]?

1054
01:15:01.934 --> 01:15:05.934
>> It is recommended that you
request

1055
01:15:05.934 --> 01:15:10.934
the actual salary of the time of
submission. Often times when

1056
01:15:10.934 --> 01:15:16.000
the salary will increase after
application has submitted if it

1057
01:15:16.000 --> 01:15:21.000
is requested of all cost over
Sally, that would be taken into
consideration

1058
01:15:21.000 --> 01:15:26.934
the and any overage will be
taken out.

1059
01:15:26.934 --> 01:15:32.934
>> Is a strategic plan from 2015
to 2020?

1060
01:15:32.934 --> 01:15:37.934
>> That RFA refers to the SRP's

1061
01:15:37.934 --> 01:15:40.934
strategic plan of 2015 through
2020.

1062
01:15:40.934 --> 01:15:43.934
>> Is there an annual increase
in

1063
01:15:43.934 --> 01:15:47.934
budget allowed [ Indiscernible -
low volume ]?

1064
01:15:47.934 --> 01:15:52.934
>> You can request a 2%
escalation

1065
01:15:52.934 --> 01:15:58.934
in the budget, please note NIH
is not allowing it. It will be
removed

1066
01:15:58.934 --> 01:16:01.934
you are selected for funding.

1067
01:16:01.934 --> 01:16:04.934
>> Thank you.

1068
01:16:04.934 --> 01:16:08.934
The next question, are the
training

1069
01:16:08.934 --> 01:16:11.934
efforts expected to be
innovative?

1070
01:16:11.934 --> 01:16:14.000
>> The short answer is yes.

1071
01:16:14.000 --> 01:16:20.000
Not exactly stated that if you
can be innovated with the

1072
01:16:20.000 --> 01:16:21.000
Cheney's, and -- trainees.

1073
01:16:21.000 --> 01:16:27.000
[ Indiscernible - multiple
speakers ] you need to be
innovative

1074
01:16:27.000 --> 01:16:32.000
within your project as well.
Innovation will be seen very
highly.

1075
01:16:32.000 --> 01:16:36.000
>> If submitting your
resubmission, do

1076
01:16:36.000 --> 01:16:40.000
we follow both resubmission and
renewal instructions within the

1077
01:16:40.000 --> 01:16:43.000
RSP?

1078
01:16:43.000 --> 01:16:47.000
>> I encourage you to talk to
your assigned program officer

1079
01:16:47.000 --> 01:16:51.000
about that. There are certain
sections -- for the most part
you

1080
01:16:51.000 --> 01:16:54.000
will follow the resubmission
guidelines.

1081
01:16:54.000 --> 01:17:00.000
You may's the sum aspects as a
renewal, you may --

1082
01:17:00.000 --> 01:17:06.000
aspects. You may include prior
years, particularly for anyone

1083
01:17:06.000 --> 01:17:09.000
on the A1 resubmission.

1084
01:17:09.000 --> 01:17:13.000
>> Contact your PO if you have
any

1085
01:17:13.000 --> 01:17:16.000
specific questions about it.

1086
01:17:16.000 --> 01:17:21.000
>> [ Indiscernible ]

1087
01:17:21.000 --> 01:17:23.934
>> Yes.

1088
01:17:23.934 --> 01:17:32.934
>> Research

1089
01:17:32.934 --> 01:17:37.934
translation on projects length
to those [ Indiscernible ]

1090
01:17:37.934 --> 01:17:42.934
research translation doesn't
expand the overall theme

1091
01:17:42.934 --> 01:17:45.934
of the program -- does it?

1092
01:17:45.934 --> 01:17:49.934
>> I need to understand the
question.

1093
01:17:49.934 --> 01:17:53.934
If we do not answer your
question correctly,

1094
01:17:53.934 --> 01:17:58.934
please resubmit if we are not
answering what you are asking.
You are asking

1095
01:17:58.934 --> 01:18:02.934
where we put the research
translation focus. You need to
make sure each

1096
01:18:02.934 --> 01:18:07.934
project has investigated
initiative translation

1097
01:18:07.934 --> 01:18:19.000
strategy and efforts coming
through individually.

1098
01:18:19.000 --> 01:18:23.934
By default it will also be as a
part of the whole center.

1099
01:18:23.934 --> 01:18:26.934
>> Okay.

1100
01:18:26.934 --> 01:18:31.934
What is the total allowed for
DMAC?

1101
01:18:31.934 --> 01:18:37.934
>> We do not have
[ Indiscernible ] individual
centers will be at

1102
01:18:37.934 --> 01:18:42.934
different levels of
[ Indiscernible ] in terms of
their

1103
01:18:42.934 --> 01:18:47.934
analysis we would expect the
budget to come in as appropriate

1104
01:18:47.934 --> 01:18:50.934
for the -- for how long far they
are for

1105
01:18:50.934 --> 01:18:53.934
their Knaus.

1106
01:18:53.934 --> 01:18:57.934
>> -- Analysis.

1107
01:18:57.934 --> 01:19:01.934
>> Can you comment on the
leadership

1108
01:19:01.934 --> 01:19:05.934
of the center, areas of
expertise or research groups

1109
01:19:05.934 --> 01:19:08.934
[ Indiscernible ]?

1110
01:19:08.934 --> 01:19:11.934
>> Yes.

1111
01:19:11.934 --> 01:19:15.000
The director is the PI that will
submit the application. But I
think

1112
01:19:15.000 --> 01:19:19.000
for some other discussion, it is
best that you contact us so we

1113
01:19:19.000 --> 01:19:23.934
can give you more guidance about
the expertise and experience and

1114
01:19:23.934 --> 01:19:27.934
again, typically center
directors are pretty well

1115
01:19:27.934 --> 01:19:31.934
versed in writing grants, as
well as other centers.

1116
01:19:31.934 --> 01:19:34.934
>> Okay.

1117
01:19:34.934 --> 01:19:38.934
Do we contact [ Indiscernible ]
about

1118
01:19:38.934 --> 01:19:40.934
the questions on content?

1119
01:19:40.934 --> 01:19:43.934
For example, the training Corps?

1120
01:19:43.934 --> 01:19:49.934
[ Indiscernible ] diversity
recruitment?

1121
01:19:49.934 --> 01:19:52.934
[ Indiscernible ]

1122
01:19:52.934 --> 01:19:57.934
>> Again, the research --
training

1123
01:19:57.934 --> 01:20:03.934
Corps is the research experience
and [ Indiscernible ]. No longer

1124
01:20:03.934 --> 01:20:04.934
25 pages.

1125
01:20:04.934 --> 01:20:10.934
We do not follow the
[ Indiscernible ] format. More
or less the same

1126
01:20:10.934 --> 01:20:15.000
format as the other core. And if
you have a specific

1127
01:20:15.000 --> 01:20:18.000
question, contact the program
officer.

1128
01:20:18.000 --> 01:20:23.934
>> [ Indiscernible ]

1129
01:20:23.934 --> 01:20:28.934
>> When you doing

1130
01:20:28.934 --> 01:20:32.934
escalation this includes salary
increases?

1131
01:20:32.934 --> 01:20:38.934
>> Yes.

1132
01:20:38.934 --> 01:20:45.934
>> Okay.

1133
01:20:45.934 --> 01:20:47.934
The indirect cost on contracts
does it count toward a cap on
allowable

1134
01:20:47.934 --> 01:20:50.934
direct cost of the program?

1135
01:20:50.934 --> 01:20:56.934
>> No.

1136
01:20:56.934 --> 01:21:01.934
As stated earlier, the consortia
call is excluded

1137
01:21:01.934 --> 01:21:06.934
from the cap Max
[ Indiscernible ]

1138
01:21:06.934 --> 01:21:22.000
>> Okay.

1139
01:21:22.000 --> 01:21:32.934
I am going to go back to the
other ones.

1140
01:21:32.934 --> 01:21:37.934
>> The question, that RFA states
under

1141
01:21:37.934 --> 01:21:42.934
the research strategy section,
the following steps actions are
recommended

1142
01:21:42.934 --> 01:21:47.934
significance and relevance of
the fund investigated approach

1143
01:21:47.934 --> 01:21:49.934
integration.

1144
01:21:49.934 --> 01:21:54.934
A similar list is recommended
for the overall component.

1145
01:21:54.934 --> 01:21:58.934
The questions are due these
subsections together need to be
within the 12

1146
01:21:58.934 --> 01:22:02.934
page limit set for the research
strategy section, which

1147
01:22:02.934 --> 01:22:06.934
contains only significant
approach subsections?

1148
01:22:06.934 --> 01:22:15.000
>> I believe

1149
01:22:15.000 --> 01:22:19.000
that all would be included in
the research strategy section.
The

1150
01:22:19.000 --> 01:22:22.000
12 pages.

1151
01:22:22.000 --> 01:22:26.934
>> How the recommended
subsections apply to the
research

1152
01:22:26.934 --> 01:22:29.934
strategy section of optional
support?

1153
01:22:29.934 --> 01:22:35.934
Relating to an earlier question.

1154
01:22:35.934 --> 01:22:39.934
The course are not going to be
getting the criterion score,

1155
01:22:39.934 --> 01:22:45.934
[ Indiscernible ] in Bashan

1156
01:22:45.934 --> 01:22:53.934
-- investigation approach.

1157
01:22:53.934 --> 01:22:55.934
It does not mean that you do not
want to include those as a part

1158
01:22:55.934 --> 01:22:58.934
of your core, it is not broken
down that way like a project is.
Again,

1159
01:22:58.934 --> 01:23:01.934
we ask that you look at the
research strategy description in
the RFA

1160
01:23:01.934 --> 01:23:08.934
for your component, and make
sure you include all sections
that are

1161
01:23:08.934 --> 01:23:14.000
requested or required for that
particular core. Also,

1162
01:23:14.000 --> 01:23:19.000
be sure to check the review
section 4 your core criteria and
make sure

1163
01:23:19.000 --> 01:23:23.934
you include sections to address
all things that there reviewer
will

1164
01:23:23.934 --> 01:23:29.934
look for. It is a lot of to the
investigator, to put

1165
01:23:29.934 --> 01:23:31.934
that together.

1166
01:23:31.934 --> 01:23:34.934
[ Indiscernible ]

1167
01:23:34.934 --> 01:23:37.934
>> Okay.

1168
01:23:37.934 --> 01:23:41.934
For investigation, this is
typically the [ Indiscernible ]

1169
01:23:41.934 --> 01:23:46.934
asked to add a section to a
research strategy section on
investigators,

1170
01:23:46.934 --> 01:23:49.934
is that correct?

1171
01:23:49.934 --> 01:23:55.934
>> We even iterate that you
should not

1172
01:23:55.934 --> 01:23:58.934
repeat what is in the bio
sketch.

1173
01:23:58.934 --> 01:24:03.934
As far as it being related to
having the ability to accomplish

1174
01:24:03.934 --> 01:24:06.934
this it will be important that
you mentioned me

1175
01:24:06.934 --> 01:24:08.934
something. It is important that
there is no overlap with the bio

1176
01:24:08.934 --> 01:24:11.934
sketch.

1177
01:24:11.934 --> 01:24:18.000
>> Okay.

1178
01:24:18.000 --> 01:24:22.000
Whatever new elements of the
community engagement core?

1179
01:24:22.000 --> 01:24:27.934
>> Have you referred to

1180
01:24:27.934 --> 01:24:30.934
the RFA?

1181
01:24:30.934 --> 01:24:34.934
And an emphasis on intervention
prevention strategy

1182
01:24:34.934 --> 01:24:37.934
to reduce the [ Indiscernible ]?

1183
01:24:37.934 --> 01:24:40.934
Please refer to the RFA.

1184
01:24:40.934 --> 01:24:45.934
>> We tried within the
presentation,

1185
01:24:45.934 --> 01:24:48.934
anything that was new our
exchange, we try to point that
out in a red

1186
01:24:48.934 --> 01:24:51.934
font.

1187
01:24:51.934 --> 01:24:56.934
>> One more thing, just

1188
01:24:56.934 --> 01:25:01.934
to note, something that Britney
emphasized. If there

1189
01:25:01.934 --> 01:25:06.934
is biological or environmental
sample collection as art of
community

1190
01:25:06.934 --> 01:25:11.934
engagement core, we really want
to see those methodologies
mentioned

1191
01:25:11.934 --> 01:25:15.000
as a part of an approach.

1192
01:25:15.000 --> 01:25:19.000
And that is described in the
RFA.

1193
01:25:19.000 --> 01:25:26.934
>> [ Indiscernible ] do we
respond

1194
01:25:26.934 --> 01:25:29.934
to a critique as an
introduction?

1195
01:25:29.934 --> 01:25:32.934
>> Yes.

1196
01:25:32.934 --> 01:25:35.934
>> Okay.

1197
01:25:35.934 --> 01:25:39.934
Is there an order to the core?
Does the

1198
01:25:39.934 --> 01:25:42.934
[ Indiscernible ] come before
the DMAC?

1199
01:25:42.934 --> 01:25:48.934
>> It is important that you
follow what is with the RFA.
[ Indiscernible ]

1200
01:25:48.934 --> 01:25:51.934
whatever makes sense.

1201
01:25:51.934 --> 01:25:57.934
>> For that [ Indiscernible ]
should

1202
01:25:57.934 --> 01:26:02.934
include [ Indiscernible - low
volume ] under the project

1203
01:26:02.934 --> 01:26:05.934
[ Indiscernible ]?

1204
01:26:05.934 --> 01:26:11.934
>> Would you like to try to
answer

1205
01:26:11.934 --> 01:26:15.000
that?

1206
01:26:15.000 --> 01:26:18.000
>> Sure, under the animal
section, you should

1207
01:26:18.000 --> 01:26:21.000
supply that information.

1208
01:26:21.000 --> 01:26:26.000
>> I would think that within the
project, you

1209
01:26:26.000 --> 01:26:31.000
would want to's day what has
been approved. And you might
want to

1210
01:26:31.000 --> 01:26:35.000
reiterate that when you talk
about the core, and it shows
cross talk

1211
01:26:35.000 --> 01:26:38.000
between project.

1212
01:26:38.000 --> 01:26:44.000
>> If I am not mistaken, this is
a just-in-time issue with

1213
01:26:44.000 --> 01:26:47.000
[ Indiscernible ].

1214
01:26:47.000 --> 01:26:51.000
You do not have your
[ Indiscernible ] approval.

1215
01:26:51.000 --> 01:26:55.000
It would be asked for once an
award and/or before

1216
01:26:55.000 --> 01:26:58.000
an award is made.

1217
01:26:58.000 --> 01:27:03.000
>> When does the first open

1218
01:27:03.000 --> 01:27:06.000
-- opening for uploading
documents?

1219
01:27:06.000 --> 01:27:13.000
>> It would be

1220
01:27:13.000 --> 01:27:16.000
whenever the receipt date of the
application is.

1221
01:27:16.000 --> 01:27:19.000
>> [ Indiscernible - multiple
speakers ] also that is the

1222
01:27:19.000 --> 01:27:22.000
start date.

1223
01:27:22.000 --> 01:27:27.934
>> November 19.

1224
01:27:27.934 --> 01:27:31.934
>> This is a good opportunity to
remind

1225
01:27:31.934 --> 01:27:36.934
people, a great resource,
especially in the heat of
putting in the application,

1226
01:27:36.934 --> 01:27:39.934
it is to call but E.R.A.
helpdesk.

1227
01:27:39.934 --> 01:27:44.934
They are up to date on all the
nuances,

1228
01:27:44.934 --> 01:27:49.934
and how you put your application
from all the many word
documents,

1229
01:27:49.934 --> 01:27:54.934
and update -- [ No audio ].

1230
01:27:54.934 --> 01:27:59.934
The phone number and email
address should be handy as we
get close

1231
01:27:59.934 --> 01:28:02.934
to the October, November and
December.

1232
01:28:02.934 --> 01:28:08.934
>> It is now 12:30.

1233
01:28:08.934 --> 01:28:14.000
I want to make sure everyone is
aware of the URL links.

1234
01:28:14.000 --> 01:28:20.000
And on the seminar research page
we have

1235
01:28:20.000 --> 01:28:23.000
topics applicable.

1236
01:28:23.000 --> 01:28:28.934
Replace these seminars and
archives. And we will have

1237
01:28:28.934 --> 01:28:30.934
those available.

1238
01:28:30.934 --> 01:28:34.934
I would like to remind everyone,
there are various ways to stay
connected,

1239
01:28:34.934 --> 01:28:40.934
to ensure that you do not miss a
webinar. For more information,

1240
01:28:40.934 --> 01:28:42.934
please refer to the website.

1241
01:28:42.934 --> 01:28:45.934
You can subscribe to monthly
newsletters.

1242
01:28:45.934 --> 01:28:50.934
You can follow on phase, twitter
and LinkedIn.

1243
01:28:50.934 --> 01:28:53.934
-- Facebook.

1244
01:28:53.934 --> 01:28:59.934
>> You can follow SRP on
Twitter.

1245
01:28:59.934 --> 01:29:05.934
With that, if you have submitted

1246
01:29:05.934 --> 01:29:09.934
an online question and we did
not get to it, we will follow

1247
01:29:09.934 --> 01:29:15.000
up with you. You can also
contact us via email. It is on
the

1248
01:29:15.000 --> 01:29:21.000
seminar homepage. That concludes
our visitation. Thank you all.

1249
01:29:21.000 --> 01:29:26.000
-- Presentation.